Founded in 1866, the American Society for the Prevention of Cruelty to Animals (ASPCA) was the first humane organization established in the Western Hemisphere and today has one million supporters. The ASPCA's mission is to provide effective means for the prevention of cruelty to animals throughout the United States. The ASPCA provides national leadership in anti-cruelty, animal behavior, humane education, government affairs and public policy, shelter support, and animal poison control. The NYC headquarters houses a full-service animal hospital and adoption facility. The Humane Law Enforcement department enforces New York's animal cruelty laws and is featured on the reality television series Animal Precinct on Animal Planet.

Wildlife Alliance's mission is to protect and preserve wildlife, forests and oceans for future generations. We are an international non-profit conservation and wildlife protection organization headquartered in Washington, D.C. with field offices and partnerships in Cambodia, Thailand, and the Russian Far East. Our field staff train and equip park rangers to fight poaching and illegal habitat destruction and work with governments, regional law enforcement officials, and communities to stop wildlife trafficking in Southeast Asia and Russia. We improve the management of protected areas, support sustainable development initiatives, and empower countries to enforce trans-boundary wildlife regulations. Wildlife Alliance also raises public awareness about environmental issues and supports local communities through sustainable development and alternative livelihoods.